Clinical Trials

Clinical trials

Clinical trials are research studies in which people help doctors find ways to improve health and cancer

 
Cancer
A general term used to describe more than 100 different disorders in which cells divide uncontrollably; and may invade nearby tissues and spread through the bloodstream and lymphatic system to other parts of the body.
care. Each study tries to answer scientific questions and to find better ways to prevent, diagnose, or treat cancer.

A clinical trial

 
Clinical Trial
In the U.S., clinical trials conducted under the supervision of the FDA
 
FDA; Food and Drug Administration
The government agency responsible for approving food and drugs for commercial distribution in the U.S.
to test effectiveness, tolerability, and safety of drugs or treatments must be satisfactorily completed prior to the FDA granting license for the product to be brought to market.
is one of the many stages of a long and careful cancer research process. Studies are done with cancer patients to find out whether promising approaches to cancer prevention, diagnosis, and treatment are safe and effective.

These trials generally occur after extensive work has been done by Raven with our agents in the laboratory and in animal studies. Regulated by the Food and Drug Administration (FDA) and other regulatory agencies around the world, clinical trials are an established way to find agents that are safe and effective.

Information on clinical trials

NCI clinical trials information page

RAV12 clinical trials

RAV12 is being studied in a Phase 1, open-label, dose-escalation clinical trial at three leading oncology

 
Oncology
The study of the causes and treatments of cancer.
centers in the United States. This trial will include approximately 30 patients with colon, stomach or pancreatic cancer, or other target
 
Target
Molecules, parts of molecules, molecular processes, and constituents of molecular processes that can be affected by a drug. The best targets tend to have the greatest degree of specificity.
antigen
 
Antigen
Any substance that can be recognized by the immune system and induce the production of antibodies. Antigens include proteins and other molecules on the surface of bacteria, viruses, cancer cells, and other foreign tissues and are the targets to which antibodies bind.
positive adenocarcinomas, including breast, lung and prostate. The on-going Phase 1 trial is designed to measure the safety and tolerability of RAV12.

For information on RAV12 Phase 1 clinical trials contact the National Cancer Institue at 1-800-4-CANCER or visit the web page below.

Information on RAV12 Phase 1 clinical trial

NCI RAV12 information page