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Type 1 Diabetes

Recently diagnosed with Type 1 Diabetes? Take action. 
Learn more: teplizumab
Learn more: ClinicalTrials.gov

Learn more: Protégé Encore site

West Nile Virus

West Nile Virus Phase 2 clinical study.
Learn more: ClinicalTrials.gov Learn more: MGAWN1

Corporate Overview

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Partnering

MacroGenics is pursuing alliances to participate in development of its proprietary product candidates and technology platforms.

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Company Highlights

  • Robust pipeline in autoimmunity, oncology and infectious diseases
  • Global partnership with Eli Lilly for development of teplizumab
  • Fully-integrated biologics capabilities across product development process 
  • Strong financial position and blue-chip investor base
  • Experienced management team and highly collaborative corporate culture 
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Home»Pipeline

Product Pipeline

MacroGenics has a diverse portfolio of product candidates with several clinical trials currently underway or planned for the near future.  Set forth below is the company's development pipeline.

 

Program (Target) Indication Lead Opt. Pre-Clin. Phase 1 Phase 2 Phase 3
AUTOIMMUNE          
Teplizumab* (CD3) Type 1 Diab. (PROTÉGÉ) *  *  *  *  * 
Pre-Diabetes (anticipated) *  *  *  *  * 
Islet Transplantation *  *  *  *  * 
2nd Indication *  *  *  *  * 
DART mAb (Undis.) Inflammation *  *  *  *  * 
ONCOLOGY          
MGAH22 (HER2) Breast, other Solid Tumors *  *  *  *  * 
DART mAb (Undis.) Multiple Solid Tumors *  *  *  *  * 
mAb (Undis.) Multiple Solid Tumors *  *  *  *  * 
INFECTIOUS DISEASES          
MGAWN1  West Nile Virus *  *  *  *  * 
Various Pathogens  Smallpox, Dengue, H5N1 *  *  *  *  * 
* In global collaboration with Eli Lilly & Co.